I am 49 years old and have started to develop hot flashes and mood changes. Is there any medication that can make these symptoms go away?

Conjugated estrogens are usually prescribed for women who are unable to produce their own sex hormones, like during menopause. Conjugated estrogens are also prescribed to prevent bone loss, after a hysterectomy and for the treatment of certain cancers in men and women (e.g. metastatic breast cancer, prostate cancer).  Conjugated estrogens are very effective at relieving symptoms of menopause like vaginal dryness, headache, depression and facial flushing. There are many formulations of conjugated estrogen varying from topical patches, oral pills and vaginal creams. All women who take conjugated estrogens must be followed up by a doctor to ensure safety and prompt recognition of side effects. The decision to take these pills rests between you and your doctor, but I highly recommend you read about these pills first.