Conjugated estrogens will resolve your hot flashes, but they also have a number of side effects. These pills can cause headaches, stomach upset, bloating nausea, weight gain, altered libido, or breast tenderness. These effects generally subside with time, but if they persist, one should speak to the doctor. In rare cases, conjugated estrogen can also cause mood changes like depression, unusual vaginal bleeding, yellowish discoloration of skin or eyes, worsening of blood sugars and difficulty controlling seizures.
Like all medications, conjugated estrogens can also cause an allergic reaction that may present as a skin rash, itching or difficulty breathing. All women who take conjugated estrogens should be aware that these medications can increase risk of blood clots that may present as calf swelling, difficulty breathing or chest pain.
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